Bioorganic and Medicinal Chemistry Letters p. 87 - 92 (1996)
Update date:2022-08-02
Topics:
Gauthier, Jacques Yves
Leblanc, Yves
Black, W. Cameron
Chan, Chi-Chung
Cromlish, Wanda A.
Gordon, Robert
Kennedey, Brian P.
Lau, Cheuk K.
Leger, Serge
Wang, Zhaoyin
Ethier, Diane
Guay, Jocelyne
Mancini, Joseph
Riendeau, Denis
Tagari, Philip
Vickers, Philip
Wong, Elizabeth
Xu, Lijing
Prasit, Peptiboon
The thiophene ring of DuP 697 was replaced by a variety of heterocycles and the products were tested for their ability to inhibit human Cox-2 and Cox-1, the isozymes of cyclooxygenase.
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