THE ESTER ENOLATE CLAISEN REARRANGEMENT. TOTAL SYNTHESIS OF (+/-)-ETHISOLIDE

DOI: 10.1016/S0040-4039(00)85501-X

Source and publish data:

Tetrahedron Letters p. 445 - 448 (1986)

Update date:2022-07-30

Topics:

Authors:

Burke, Steven D.

Pacofsky, Gregory J.

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Article abstract of DOI:10.1016/S0040-4039(00)85501-X

A total synthesis of the mold metabolite ethisolide (1a) is described, wherein a glycolate ester enolate Claisen rearrangement and an acid-induced intramolecular bis-transesterification are key steps.

Full text of DOI:10.1016/S0040-4039(00)85501-X

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