THE ESTER ENOLATE CLAISEN REARRANGEMENT. TOTAL SYNTHESIS OF (+/-)-ETHISOLIDE

DOI: 10.1016/S0040-4039(00)85501-X

Source and publish data:

Tetrahedron Letters p. 445 - 448 (1986)

Update date:2022-07-30

Topics:

Authors:

Burke, Steven D.

Pacofsky, Gregory J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)85501-X

A total synthesis of the mold metabolite ethisolide (1a) is described, wherein a glycolate ester enolate Claisen rearrangement and an acid-induced intramolecular bis-transesterification are key steps.

Full text of DOI:10.1016/S0040-4039(00)85501-X

Products guided by the article

Product name:(R)-((2S,3R)-2-Ethyl-5-oxo-4-phenylsulfanylmethyl-tetrahydro-furan-3-yl)-(2-trimethylsilanyl-ethoxy)-acetic acid methyl ester

Cas No:104206-44-2

R&D Labs maybe for 104206-44-2

KindChem Co.,Ltd,

Contact:+86-25-85281586

Address:13F,Bld2#,South of Longpan Road
Chengdu NoVi Biotechnology Co., Ltd.(expird)

Contact:13551243286/028-81458053

Address:NO.168-1-224 JULONG ROAD WUHOU DISTRICT, CHENGDU CITY,SICHUAN PROVINCE
Zhuhai Jiacheng Biological Technology Co., Ltd

Contact:0756-8800233

Address:room 222, Lianhua road , Gongbei ,Zhuhai, Guangdong ,China
Changzhou BaoKang Pharmaceutical & Chemical Co., Ltd

Contact:(86) 519-88782201 88784080 88785278

Address:Henglin town, changzhou,Jiangsu
Zhengzhou Yuanli Biological Technology Co., Ltd.

Contact:+86-371-67897870/67897895

Address:No. 38, Qingyang Street, Zhengzhou, Henan, China

Relevant to this article

Homoleptic selenium cyanides: Attempted preparation of Se(CN)₄ and redetermination of the crystal structure of Se(CN)₂

Doi:10.1021/ic801011g
(2008)
Preparation of anti-tetracycline antibodies and development of an indirect heterologous competitive enzyme-linked immunosorbent assay to detect residues of tetracycline in milk

Doi:10.1021/jf062627s
(2007)
Novel amidino-substituted thienyl- and furylvinylbenzimidazole: Derivatives and their photochemical conversion into corresponding diazacyclopenta[c] fluorenes. Synthesis, interactions with DNA and RNA, and antitumor evaluation

Doi:10.1021/jm8000423
(2008)
Profiling small molecule inhibitors against helix-receptor interactions: The Bcl-2 family inhibitor BH3I-1 potently inhibits p53/hDM2

Doi:10.1039/c0cc02969f
(2010)
Ultrasound-assisted and efficient knoevenagel condensation reaction catalyzed by silica sodium carbonate nanoparticles

Doi:10.5562/cca3261
(2018)
Synthesis of 4-Oxoisoxazoline N-Oxides via Pd-Catalyzed Cyclization of Propargylic Alcohols with tert-Butyl Nitrite

Doi:10.1021/acs.orglett.9b00811
(2019)

Article Doi