Organic Letters p. 8543 - 8547 (2019)
Update date:2022-09-26
Topics:
Zhou, Lan
Shen, Yao-Bin
An, Xiao-De
Li, Xian-Jiang
Li, Shuai-Shuai
Liu, Qing
Xiao, Jian
Herein, we report the first redox-neutral and transition-metal-free β-C(sp3)-H functionalization of cyclic amines via a consecutive intermolecular hydride transfer process. A series of N-aryl pyrrolidines and N-aryl 1,2,3,4-tetrahydropyridines decorated with CF3 and carboxylic ester functionalities are directly accessed in good yields from pyrrolidines and piperidines. This work pushes forward the application of the intermolecular hydride transfer strategy in one-step assembly of molecular complexity.
View MoreAnqing World Chemical Co., Ltd.
Contact:+86-556-5800026
Address:Daguan Economic Development Zone of circular economy industrial park Anqing City Anhui province
Beijing Merson Pharmaceutical Co., Ltd
Contact:0086-10-80484934 0086-10-80484574/
Address:2nd Floor , No. 2 Building , No. 14 Houshayu Duan, Jingmi Road ,Shunyi District , Beijing 101318, P.R.China
Shanghai Forever Biotech Co., Ltd.
Contact:+86-21-69734790
Address:Room 5017/5019、5022、5024 of Technology Innovation Centre, No.1155, Gongyuan East Rd, QingPu District, Shanghai China.
Wuxi Morality Chemical Co., Ltd(expird)
Contact:
Address:B/7F, 321th WuYun Rd, Wanda Plaza, Wuxi City, 214174, China
ShangHai Ruiyi Medical Technology Co.,Ltd.
Contact:+86-21-54718086
Address:No951 Jianchuan RD，Minhang District
Doi:10.1016/j.ejmech.2008.09.039
(2009)Doi:10.1021/ja00237a037
(1987)Doi:10.1016/S0040-4039(01)84576-7
(1985)Doi:10.1248/cpb.33.4821
(1985)Doi:10.1016/S0040-4039(00)84644-4
(1986)Doi:10.1055/s-1986-31486
(1986)
