THE HIGHLY STEREOSELECTIVE SYNTHESIS OF ALL-TRANS AND 13-CIS VITAMIN A VIA DOUBLE ELIMINATION REACTION

Article abstract of DOI:10.1246/cl.1985.1883

Stereocontrolled convergent synthesis of vitamin A was achieved by the double elimination method employing the C10 sulfone and the C10 aldehydes as starting materials.Thus the all-trans and 13-cis isomers were obtained with the stereochemical purity of 95percent and 90percent, respectively.