Journal of Medicinal Chemistry p. 675 - 678 (1987)
Update date:2022-07-29
Topics:
Brixner, Diana I.
Ueda, Takamori
Cheng, Yung-Chi
Hynes, John B.
Broom, Arthur D.
Recent demonstrations that deazafolate analogues may act as potent inhibitors of thymidylate synthase (TS) provided a firm rationale for the synthesis of N10-propargyl derivatives of 8-deazafolate (3) and 8-deazaaminopterin (4).A complete assig
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