Estrogenic Affinity Labels: Synthesis, Irreversible Receptor Binding, and Bioactivity of Aziridine-Substituted Hexestrol Derivatives

DOI: 10.1021/jm00388a015

Source and publish data:

Journal of Medicinal Chemistry p. 829 - 838 (1987)

Update date:2022-07-31

Topics:

Authors:

Zablocki, Jeffery A.

Katzenellenbogen, John A.

Carlson, Kathryn E.

Norman, M. J.

Katzenellenbogen, Benita S.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00388a015

To develop an affinity label for the estrogen receptor that would be an estrogen agonist, rather than antagonist, we prepared several aziridine derivatives of the potent nonsteroidal estrogen hexestrol (3R^*,4S^*)-3,4-bis(4-hydroxyphen

Full text of DOI:10.1021/jm00388a015

Products guided by the article

Product name:(2R*,3S*)-2,3-bis<4-(tert-butyldimethylsiloxy)phenyl>pentyl carbethoxymethyl sulfide

Cas No:107036-31-7

R&D Labs maybe for 107036-31-7

Tangshan Moneide Trading Co., Ltd.

Contact:+86-315-8309571

Address:2-7-420 Jidong Building Materials Commercial Center, Tangshan, Hebei, 064000 China
Jiangxi Hessence Chemicals Co., Ltd.

Contact:+86 796 3511924

Address:Chengxi Industrial Park, Jishui County, Jiangxi Province 331600 China.
HANGZHOU GOPHER CHEM-TECH CO.,LTD

Contact:86-189-58111780

Address:Da Cheng Ming Zuo Plaza,Xiaoshan District
Huangshi Meifeng Chemical Co.,ltd.

Contact:+86-714-6516706

Address:1941-4-3#,Hubin Avenue,Huangshi,Hubei,China
JiangXi Hong Run Chemical Co., Ltd

Contact:+86-0791-88521351

Address:XingHuo industrial zone in YongXiu county

Relevant to this article

Supramolecular luminescent gold(I)-copper(I) complexes: Self-assembly of the Au_xCu_y clusters inside the [Au ₃(diphosphine)₃]³⁺ triangles

Doi:10.1021/ic801073k
(2008)
Cruciform oligo(phenylenevinylene) with a bipyridine bridge: Synthesis, its rhenium(I) complex and photovoltaic properties

Doi:10.1039/b804995e
(2008)
An osteoclast-targeting agent for imaging and therapy of bone metastasis

Doi:10.1016/j.bmcl.2008.07.092
(2008)
Heterogeneous biomimetic aerobic synthesis of 3-iodoimidazo[1,2-a]pyridines via CuO_x/OMS-2-catalyzed tandem cyclization/iodination and their late-stage functionalization

Doi:10.1039/c4cy00919c
(2015)
Electron- or hole-transporting nature selected by side-chain-directed π-stacking geometry: Liquid crystalline fused metalloporphyrin dimers

Doi:10.1021/ja201272t
(2011)
Diene hydroacylation from the alcohol or aldehyde oxidation level via ruthenium-catalyzed C-C bond-forming transfer hydrogenation: Synthesis of β,γ-unsaturated ketones

Doi:10.1021/ja805356j
(2008)

Article Doi