A NOVEL AND STEREOSELECTIVE SYNTHESIS OF (+/-)-CEPHALOTAXINE AND ITS ANALOGUE

DOI: 10.1016/S0040-4039(00)84438-X

Source and publish data:

Tetrahedron Letters p. 2023 - 2026 (1986)

Update date:2022-09-26

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Authors:

Yasuda, Shingo

Yamada, Toru

Hanaoka, Miyoji

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Article abstract of DOI:10.1016/S0040-4039(00)84438-X

Cephalotaxine (1) and its analogue (3) were stereoselectively synthesized from proline via the pyrrolobenzazepine (4) through Claisen rearrangement, cationic cyclization, and regio- and stereo-selective hydroxylation.

Full text of DOI:10.1016/S0040-4039(00)84438-X

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