PALLADIUM- OR NICKEL-CATALYZED REACTION OF ALKYNES WITH TRIMETHYLSILYL CYANIDE. A NEW SYNTHESIS OF 5-AMINOPYRROLE-2-CARBONITRILES

DOI: 10.1016/S0040-4039(00)84949-7

Source and publish data:

Tetrahedron Letters p. 4201 - 4204 (1986)

Update date:2022-07-31

Topics:

Authors:

Chatani, Naoto

Hanafusa, Terukiyo

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)84949-7

The reaction of alkynes with trimethylsilyl cyanide (1) in the presence of a palladium or nickel catalyst gave 5-aminopyrrole-2-carbonitriles in high yields with high regioselectivity.

Full text of DOI:10.1016/S0040-4039(00)84949-7

Products guided by the article

Product name:5-(1,1,1,3,3,3-Hexamethyl-disilazan-2-yl)-3-(4-methoxy-phenyl)-4-phenyl-1H-pyrrole-2-carbonitrile

Cas No:107906-29-6

R&D Labs maybe for 107906-29-6

shanghai jiuling chemical co.,ltd.

Contact:+86-21-50387295

Address:Zaozhuang Road, Pudong, Shanghai City. China
ENERGYCO LTD.

Contact:+86-25-83719363

Address:106-7 Chunnan Rd, Chunxi Town, Gaochun, Nanjing, China
Nanjing Legend Pharmaceutical & Chemical Co., Ltd.

Contact:+86-25-83767696

Address:14-7 Zhongshan Lu Guluo District, Nanjing
MS( MAOSHENG )Chemical CO.,LTD

Contact:+86-519-82726678.82726378

Address:TAOXI INDUSTRY ZONE JINTAN
C-LAB Chemievermittlung GmbH

Contact:+49-9398-993127

Address:Untertorstr. 27

Relevant to this article

Reaction of hydantoin with boronic acids

Doi:10.1002/hlca.201000022
(2010)
(2-Fluoroallyl)boronates: New reagents for diastereoselective 2-fluoroallylboration of aldehydes

Doi:10.1039/c8ob01103f
(2018)
Synthesis and characterization of teranthene: A singlet biradical polycyclic aromatic hydrocarbon having kekule structures

Doi:10.1021/ja1049737
(2010)
OPTICALLY ACTIVE PHOSPHINE OXIDES. 8. SYNTHESIS OF NONSYMMETRICAL 1,2-DIPHOSPHINYLETHENES AND RELATED SYSTEMS

Doi:10.1016/0040-4020(89)80061-4
(1989)
TDA-1 CATALYSIS IN SMILES REARRANGAMENT OF N-ARYLPHENOXYAMIDES. ACCELERATING EFFECT OF THE 2,4,6-TRICHLORO SUBSTITUTION

Doi:10.1016/S0040-4039(00)95282-1
(1989)
An Efficient, Scalable and Eco-friendly Synthesis of 4,5-substituted Pyrrole-3-Carbonitriles by Intramolecular Annulation on Pd/C and HZSM-5

Doi:10.1002/cctc.201900154
(2019)

Article Doi