PALLADIUM- OR NICKEL-CATALYZED REACTION OF ALKYNES WITH TRIMETHYLSILYL CYANIDE. A NEW SYNTHESIS OF 5-AMINOPYRROLE-2-CARBONITRILES

DOI: 10.1016/S0040-4039(00)84949-7

Source and publish data:

Tetrahedron Letters p. 4201 - 4204 (1986)

Update date:2022-07-31

Topics:

Authors:

Chatani, Naoto

Hanafusa, Terukiyo

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)84949-7

The reaction of alkynes with trimethylsilyl cyanide (1) in the presence of a palladium or nickel catalyst gave 5-aminopyrrole-2-carbonitriles in high yields with high regioselectivity.

Full text of DOI:10.1016/S0040-4039(00)84949-7

Products guided by the article

Product name:5-(1,1,1,3,3,3-Hexamethyl-disilazan-2-yl)-3-(4-methoxy-phenyl)-4-phenyl-1H-pyrrole-2-carbonitrile

Cas No:107906-29-6

R&D Labs maybe for 107906-29-6

GLD peptide scientific lnc.

Contact:21-7631221 15884421033

Address:326 Science and technology,Shanghai,China
Shanghai Xinda Pharmaceuticals Co., Ltd.

Contact:86-21-33692333-8008

Address:999 Linxian Road, Jinshan Industrial Park, Shanghai, China
Suzhou HeChuang Chemical Co.,Ltd.

Contact:+86-512-88800520

Address:No.9 Guanchao Rd,Changshu Advanced Materials Industy Park
Nanjing Samwon International Limited

Contact:+86-25-84873444

Address:1108, BLDG B, New Century Plaza, No 1, South Taiping Rd.,
Changsha Easchem Co.,Limited

website:http://www.easchem.com

Contact:+86-731-89722861 89722891

Address:2/F-4/Bld Colorful Palace, No.605 Changsha Ave, Yuhua Area Changsha Hunan China.

Relevant to this article

Reaction of hydantoin with boronic acids

Doi:10.1002/hlca.201000022
(2010)
(2-Fluoroallyl)boronates: New reagents for diastereoselective 2-fluoroallylboration of aldehydes

Doi:10.1039/c8ob01103f
(2018)
Synthesis and characterization of teranthene: A singlet biradical polycyclic aromatic hydrocarbon having kekule structures

Doi:10.1021/ja1049737
(2010)
OPTICALLY ACTIVE PHOSPHINE OXIDES. 8. SYNTHESIS OF NONSYMMETRICAL 1,2-DIPHOSPHINYLETHENES AND RELATED SYSTEMS

Doi:10.1016/0040-4020(89)80061-4
(1989)
TDA-1 CATALYSIS IN SMILES REARRANGAMENT OF N-ARYLPHENOXYAMIDES. ACCELERATING EFFECT OF THE 2,4,6-TRICHLORO SUBSTITUTION

Doi:10.1016/S0040-4039(00)95282-1
(1989)
An Efficient, Scalable and Eco-friendly Synthesis of 4,5-substituted Pyrrole-3-Carbonitriles by Intramolecular Annulation on Pd/C and HZSM-5

Doi:10.1002/cctc.201900154
(2019)

Article Doi