Tetrahedron p. 2979 - 2984 (1986)
Update date:2022-07-30
Topics:
Garigipati, Ravi S.
Cordova, Robert
Parvez, Masood
Weinreb, Steven M.
Novel methodology for the diastereoselective synthesis of some branched functionalized homoallylic amine derivatives is described.The protocol starts with a 3,6-dihydrothiazine-1-oxide, which is readily obtained in a totally stereospecific manner by the hetero-Diels-Alder cycloaddition of an N-sulfinyl dienophile and a 1,3-diene.Various Grignard reagents have been added to these adducts to afford sulfoxide derivatives which have been manipulated stereoselectively via <2,3>-or <3,3>-sigmatropic rearrangements into branched homoallylic amines potentially useful for further synthetic transformations.
View MoreSHAANXI TOP PHARM CHEMICAL CO.LTD
Contact:+86-029-85733403
Address:No.108 ,west sector,south er huan,xi'an,china
Jinan Kaypharm Chemical Co.,Ltd
Contact:86-0531-86986780
Address:Room101,No189-2,Huayuan Road,Jinan City,Shandong Province
Xi'an yuanfar international trade company
website:https://www.yuanfarchemical.com
Contact:86-029-88745613 ext 828
Address:Floor19th ,B Building, Oak Block,No.36 South Fenghui Road, Dev. Zone of High-Tech Ind.,Xi’an, China
Tengzhou Runlong Fragrance Co., Ltd.
website:http://www.tzrunlong.com/
Contact:0086-15665710862
Address:No. 78, Fushan Road, Biomedical Industrial Park, Dawu Town, Tengzhou, Shandong, 277514 China
Weifang Yukai Chemical Co.,Ltd.
website:http://www.yukaichem.com/en.html
Contact:+86-536-8865336
Address:binhai economic development zone，262737 shangdong，china
Doi:10.1246/cl.1986.2109
(1986)Doi:10.1016/j.tetlet.2009.09.085
(2009)Doi:10.1021/jo00292a040
(1990)Doi:10.1016/S0040-4039(00)78509-1
(1994)Doi:10.1016/j.tetlet.2014.04.124
(2014)Doi:10.1021/ac00153a008
(1988)
