Bioorganic and Medicinal Chemistry Letters p. 5134 - 5139 (2008)
Update date:2022-07-29
Topics:
Pinard, Emmanuel
Alberati, Daniela
Borroni, Edilio
Fischer, Holger
Hainzl, Dominik
Jolidon, Synese
Moreau, Jean-Luc
Narquizian, Robert
Nettekoven, Matthias
Norcross, Roger D.
Stalder, Henri
Thomas, Andrew W.
Screening of the Roche compound library led to the identification of the benzoylpiperazine 7 as a structurally novel GlyT1 inhibitor. The SAR which was developed in this series resulted in the discovery of highly potent compounds displaying excellent sele
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