Synthesis p. 845 - 847 (1986)
Update date:2022-07-29
Topics:
Doyle, I. D.
Massy-Westropp, R. A.
Warren, R. F. O.
Reaction of succinic anhydride (1) with (1-ethoxycarbonylethylidene)triphenylphosphorane (2) gives ethyl 2-(5-oxotetrahydrofur-2-ylidene)propanoate 3.Compound 3 is cleaved with sodium ethoxide to the β-ketodiester anion, which is treated with alkylhalide
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