Journal of Organic Chemistry p. 3872 - 3875 (1987)
Update date:2022-08-05
Topics:
Keinan, Ehud
Eren, Doron
Highly efficient copper-catalyzed polymethoxylation of tribromocresol is the key process in a three-step, practical approach to obtain ubiquinone 0 from p-cresol.Short syntheses of several ubiquinones were achieved via direct, copper-mediated coupling of 2-lithio-3,4,5,6-tetramethoxytoluene to the appropriate polyprenyl bromide.
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