Tetrahedron Letters p. 2095 - 2098 (1986)
Update date:2022-08-03
Topics: NMR spectroscopy Catalyst HPLC Enantioselectivity Cross-coupling Protecting group Michael addition Retrosynthetic analysis Stereoselectivity Stereocontrolled Synthesis Dipeptide Peptide bond Olefination Isostere
Spaltenstein, Andreas
Carpino, Philip A.
Miyake, Fumio
Hopkins, Paul B.
A general synthetic route to trans-alkene isosteres of protected dipeptides is reported.This sequence permits the fully stereocontrolled preparation of these isosteres in optically active form and in quantities sufficient for further biological study.Prep
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Doi:10.1021/om800878m
(2009)Doi:10.1021/acs.orglett.9b00119
(2019)Doi:10.1021/jo00228a025
(1987)Doi:10.1080/00397911.2017.1359627
(2017)Doi:10.1016/S0040-4039(00)85339-3
(1986)Doi:10.1016/S0040-4039(00)85335-6
(1986)
