Thiophene Systems. 9. Thienopyrimidinedione Derivatives as Potential Antihypertensive Agents

DOI: 10.1021/jm00117a019

Source and publish data:

Journal of Medicinal Chemistry p. 1786 - 1793 (1988)

Update date:2022-08-05

Topics:

Authors:

Russell, Ronald K.

Press, Jeffrey B.

Rampulla, Richard A.

McNally, James J.

Falotico, Robert

et al. et al.

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Article abstract of DOI:10.1021/jm00117a019

A series of thieno<3,4-d>-, thieno<3,2-d>-, and thieno<2,3-d>pyrimidine-2,4-diones with (phenylpiperazinyl)alkyl substitution at N-3 have been synthesized and evaluated for antihypertensive effects in spontaneously hypertensive rats (SHR).These 49 compoun

Full text of DOI:10.1021/jm00117a019

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