Syntheses of New Optically Active Organosilanes and Their Applications for the Optical-Purity-Determining Agents

Article abstract of DOI:10.1246/bcsj.59.3581

New optically active organosilicon compounds such as (benzylmethylphenylsilyl)acetic acid (1) and (ethylmethylphenylsilyl)acetic acid (2) were synthesized.Application of these acids as the optical purity determining agents for chiral amines and alcohols were successfully carried out.In addition, it was also revealed that optically active (benzylmethylphenylsilyl)methylamine (3) and methylamine (4) are able to be used as the optical purity determining agents for chiral carboxylic acids.