Asymmetric synthesis of α,β-epoxysulfones under phase-transfer catalyzed Darzens reaction

Article abstract of DOI:10.1016/S0040-4039(98)01811-5

Enantioselective synthesis of α,β-epoxysulfones by the Darzens reaction was achieved under phase-transfer catalyzed conditions. The reaction of chloromethyl phenylsulfone with various aromatic aldehydes smoothly proceeded in the presence of a catalytic am