Potent vasopressin antagonists modified at the carboxy-terminal tripeptide tail

DOI: 10.1021/jm00395a019

Source and publish data:

Journal of Medicinal Chemistry p. 2291 - 2294 (1987)

Update date:2022-07-29

Topics:

Authors:

Ali Ali

Chang Chang

Huffman Huffman

Heckman Heckman

Kinter Kinter

Weidley Weidley

Edwards Edwards

Schmidt Schmidt

Ashton-Shue

Stassen Stassen

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00395a019

In a continuing effort to design more potent renal vasopressin (V₂ receptor) antagonists, we have focused our attention on the carboxy-terminal tripeptide tail (Pro-Arg-Gly-NH₂), a fragment common to both agonists and antagonists. Va

Full text of DOI:10.1021/jm00395a019

Products guided by the article

Product name:C₅₂H₇₉N₁₅O₁₀S₂

Cas No:110500-75-9

R&D Labs maybe for 110500-75-9

zhejiang huangyan wanfeng pharm chem co.ltd

Contact:+86-576- 84160728

Address:No. 5 Dazha Road, Economic,Development Zone(JiangKou), Zhejiang, China
Suzhou Lixin Pharmaceutical Co., Ltd.

Contact:86-512-88169812

Address:21 Tangxi Road, Suzhou New District, Suzhou 215151
Langchem

Contact:+86+21-58956006 15800617331

Address:402 Room, 150# Cailun Road, Zhangjiang high tech park, Shanghai
Jiangsu Jiuri Chemical Co.,Ltd.

Contact:+86-519-82118868

Address:Tianwang Town, Jurong City, Jiangsu Province, China
SINO GREAT ENTERPRISE LTD.

Contact:+86-731-84427351

Address:154 JIANXIANG SOUTH ROAD

Relevant to this article

A practical total synthesis of hapalosin, a 12-membered cyclic depsipeptide with multidrug resistance-reversing activity, by employing improved segment coupling and macrolactonization

Doi:10.1021/jo0497499
(2004)
β-DEUTERIUM KINETIC ISOTOPE EFFECTS IN THE SOLVOLYSIS OF 2-ARYL-1,1,1-TRIFLUORO-2-PROPYL TOSYLATES AND OF 2-ARYL-2-PROPYL p-NITROBENZOATES. EVIDENCE FOR A VARIATION OF THE CONTRIBUTION OF α-METHYL SUBSTITUENT IN STABILIZING CATIONIC REACTION CENTERS WITH DIFFERENT ELECTRON DEMAND

Doi:10.1016/S0040-4039(00)84865-0
(1986)
Directional probes of the hydrophobic component of the aromatic ring binding site of norepinephrine N-methyltransferase

Doi:10.1021/jm00352a021
(1982)
SYNTHESIS AND ANTIANDROGEN ACTIVITY OF SUBSTITUTED CARBOXYANILIDES

Doi:10.1007/BF00758631
(1987)
Efficient method for synthesis of methylene diesters using polyethylene glycol as a phase transfer catalyst

Doi:10.1080/00397919708004081
(1997)
Leukotriene Receptor Antegonist. 4. Synthesis and Leukotriene D₄/E₄ Receptor Antagonist Activity of 4-(Alkyl)acetophenone Derivatives

Doi:10.1021/jm00396a027
(1988)

Article Doi