Potent vasopressin antagonists modified at the carboxy-terminal tripeptide tail

DOI: 10.1021/jm00395a019

Source and publish data:

Journal of Medicinal Chemistry p. 2291 - 2294 (1987)

Update date:2022-07-29

Topics:

Authors:

Ali Ali

Chang Chang

Huffman Huffman

Heckman Heckman

Kinter Kinter

Weidley Weidley

Edwards Edwards

Schmidt Schmidt

Ashton-Shue

Stassen Stassen

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Article abstract of DOI:10.1021/jm00395a019

In a continuing effort to design more potent renal vasopressin (V₂ receptor) antagonists, we have focused our attention on the carboxy-terminal tripeptide tail (Pro-Arg-Gly-NH₂), a fragment common to both agonists and antagonists. Va

Full text of DOI:10.1021/jm00395a019

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