Tetrahedron p. 5887 - 5894 (1986)
Update date:2022-09-26
Topics:
Takase, Shigehiro
Uchida, Itsuo
Tanaka, Hirokazu
Aoki, Hatsuo
Itoh, Yoshikuni
A total synthesis of amauromine (1) is described.Starting with L-tryptophan, diketopiperazine 4 was synthesized in nine steps.Thio-Claisen rearrangement of the sulphonium cation derived from the key intermediate 4 proceeded at the two sites simultaneously to provide 3 along with 12.Reductive desulphurization on 3 using TiCl4-LiAlH4 (1:2) resulted in concurrent cyclization to lead to amauromine (1).
View MoreNanjing Vincero International Trading Co.,Ltd
Contact:8618936897229
Address:NO.68, ZhuShan Road, JiangNing WanDa Plaza, Building E Room 1703
Anhui Dexinjia Biopharm Co., Ltd
Contact:+86-531-82375818
Address:9 Hexie Road, kaifaqu, Taihe
wuxi huabin bio-tech Co.,Ltd(expird)
Contact:86-0510-85133006
Address:hubin road NO157
website:http://www.aecochemical.com
Contact:+86-592 599 8717
Address:No 611 Sishui Road,Huli
Shenyang Xinyihan Chemical Technology Co., Ltd.
Contact:+86-18525026267
Address:362, aigongbeijei street 23 , tiexi district,Shenyang, Liaoning, China
Doi:10.1016/S0040-4039(00)87790-4
(1986)Doi:10.1007/BF00663850
(1987)Doi:10.1016/j.tetlet.2008.11.036
(2009)Doi:10.1016/j.tet.2008.11.036
(2009)Doi:10.1021/jo01103a032
(1958)Doi:10.1002/JLCR.1676
(2009)
