
Journal of Organic Chemistry p. 955 - 963 (1988)
Update date:2022-07-29
Topics:
Padwa, Albert
Matzinger, Michael
Tomioka, Yukihiko
Venkatramanan, M. K.
Dipolar cycloaddition of nitrones with electron-deficient allenes gives 5-exo-methylene substituted isoxazolidines in high yield.The regiochemistry of the cycloaddition can be attributed to a favorable allene (LUMO)-nitrone (HOMO) interaction.The isoxazol
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