Chemistry of Heterocyclic Compounds p. 1198 - 1202 (1986)
Update date:2022-08-04
Topics:
Shachkus, A. A.
Degutis, Yu. A.
1-R-9,9,9a-Trimethyl-1,2,3,9a-tetrahydro-9H-imidazo<1,2-a>indol-2-ones and the corresponding 2-methylene-2,3-dihydroindoles were obtained by the reaction of 2,3,3-trimethyl-3H-indole with a number of N-substituted chloroacetic acid amides and subsequent reaction of the resulting quartenary salts with bases.The kinetics of intramolecular cyclization of 1-(N-alkylcarbamoylethyl)-2-methylene-2,3-dihydroindoles under the influence of acetic acid were studied.Under the influence of strong protic acids 1-R-imidazo<1,2-a>indol-2-ones undergo decyclization and are converted to 3H-indolium salts.
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Doi:10.1021/jo00235a013
(1987)Doi:10.1016/S0040-4020(01)88118-7
(1986)Doi:10.1039/b902802a
(2009)Doi:10.1021/acschembio.8b00864
(2018)Doi:10.1039/b911589g
(2009)Doi:10.1007/BF00471813
(1986)