Stereoselective Synthesis of (E)-5-Hydroxy-4-methyl-2-alkenoates by Palladium-Catalyzed Stereospecific Hydrogenolysis of (E)-4,5-Epoxy-4-methyl-2-alkenoates with Ammonium Formate

DOI: 10.1246/cl.1986.1775

Source and publish data:

Chemistry Letters p. 1775 - 1776 (1986)

Update date:2022-08-04

Topics: Stereoselective synthesis Palladium-Catalyzed Stereospecific Hydrogenolysis Ammonium Formate

Authors:

Shimizu, Isao

Oshima, Masato

Nisar, Mohammad

Tsuji, Jiro

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1246/cl.1986.1775

Palladium-catalyzed hydrogenolysis of (E)-4,5-epoxy-4-methyl-2-alkenoates with HCO2H-Et3N gave (E)-5-hydroxy-4-methyl-2-alkenoates in good yields with inversion of stereochemistry.

Full text of DOI:10.1246/cl.1986.1775

Products guided by the article

Product name:Ethyl (+/-)-(E)-(4R^*,5S^*)-5-hydroxy-4-methyl-5-phenyl-2-pentenoate

Cas No:111120-84-4

R&D Labs maybe for 111120-84-4

JiYi Chemical (Beijing) Co., Ltd.

Contact:+86-10-89385733

Address:Shilou Town of Fangshan District， Beijing
Jiangsu Seed Chem Co.,Ltd.

Contact:86-513-84128750/13773795976

Address:No.48.Youyi West Road ,Rudong Development Zone,Jiangsu Province,China
Yangzhou Zhongbao Pharmaceutical Co.,Ltd

Contact:+86-514-88290838

Address:Jiangsu Baoying county economic develpment zone in baoying avenue91
Lian Xing Chemical Co.,Ltd.

Contact:0792-8228321

Address:10TH Floor No.121 binjiang Road Xunyang District
Wuhan Shengmao Corp

website:http://www.shengmaochem.com

Contact:86-27-82853423, 82819281

Address:Rm 202, A Unit Huaqiao Building No. 2, Lihuangpi Road, Wuhan, China

Relevant to this article

Synthesis and structure of 4-R,5-R-[5-(hydroxy-diphenyl-methyl)-2, 2-dimethyl-[1,3] dioxolan-4-yl]-phenyl-methanone, a chiral ligand building block

Doi:10.1023/A:1024282114729
(2003)
The design and synthesis of substituted biphenyl libraries

Doi:10.1016/0968-0896(96)00060-0
(1996)
Doi:10.1021/ja01274a040
(1938)
A General Asymmetric Formal Synthesis of Aza-Baylis–Hillman Type Products under Bifunctional Catalysis

Doi:10.1002/chem.201705218
(2018)
Synthesis, anti-inflammatory, cytotoxic, and COX-1/2 inhibitory activities of cyclic imides bearing 3-benzenesulfonamide, oxime, and β-phenylalanine scaffolds: a molecular docking study

Doi:10.1080/14756366.2020.1722120
(2020)
Synthesis of (-)-N-acetylslaframine by C-1, C-5 bis-hydroxyalkylation of (5)-2-(N,N-dibenzylamino)-1,5-pentanediol via highly diastereoselective lithiation of the dicarbamate

Doi:10.1055/s-2007-983724
(2007)

Article Doi