Synthesis and structure-activity relationships of antiallergic N-[4-[4-(1H-indol-3-yl)piperidinoalkyl]-2-thiazolyl]alkanamides possessing both antihistaminic and anti slow-reacting substance (SRS) activities

DOI: 10.1248/cpb.42.1822

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1822 - 1827 (1994)

Update date:2022-08-03

Topics:

Authors:

Shigenaga

Manabe Manabe

Matsuda Matsuda

Fujii Fujii

Matsuo Matsuo

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Article abstract of DOI:10.1248/cpb.42.1822

A series of N-[4-[4-(1H-indol-3-yl)piperidinoalkyl]-2-thiazolyl]alkanamide derivatives were synthesized and tested for in vivo antianaphylactic activity and in vitro anti slow-reacting substance (SRS) activity. Among the compounds synthesized, N-[4-[4-(1H

Full text of DOI:10.1248/cpb.42.1822

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