Synthesis and structure-activity relationships of antiallergic N-[4-[4-(1H-indol-3-yl)piperidinoalkyl]-2-thiazolyl]alkanamides possessing both antihistaminic and anti slow-reacting substance (SRS) activities

DOI: 10.1248/cpb.42.1822

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1822 - 1827 (1994)

Update date:2022-08-03

Topics:

Authors:

Shigenaga

Manabe Manabe

Matsuda Matsuda

Fujii Fujii

Matsuo Matsuo

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.42.1822

A series of N-[4-[4-(1H-indol-3-yl)piperidinoalkyl]-2-thiazolyl]alkanamide derivatives were synthesized and tested for in vivo antianaphylactic activity and in vitro anti slow-reacting substance (SRS) activity. Among the compounds synthesized, N-[4-[4-(1H

Full text of DOI:10.1248/cpb.42.1822

NII-Electronic Library Service

Products guided by the article

Product name:1-<4-(1-phenyl-1H-indol-3-yl)piperidino>ethanone

Cas No:111608-59-4

R&D Labs maybe for 111608-59-4

Jinhua Haoyuan Chemical CO., LTD(expird)

Contact:86-579-82465583

Address:Jinhua,Zhejiang
Tianjin Emulsion Science&Technology Development Co.,Ltd

Contact:13901380442

Address:Vake Garden New Town New Yi Bai Road Beichen District Tianjin,China
Quzhou Aokai Chemical Co., Ltd.

Contact:86-570-3032832

Address:NO.16 , Laodong Road,Quzhou City, Zhejiang Province,China
Nanjing yieldpharma co.ltd

Contact:13813902930 025-52714267

Address:20 Fengji Road, Yuhua Economic Development Zone, Nanjing, Jiangsu, P. R. China
Phantom-pharma

Contact:

Address:

Relevant to this article

Doi:10.1016/0021-9517(87)90265-X
(1987)
An enzyme module system for in situ regeneration of deoxythymidine 5′-diphosphate (dTDP)-activated deoxy sugars

Doi:10.1002/adsc.200700058
(2007)
Ruthenium(IV)-Oxo Complexes: The Novel Utilization of Tertiary Pnictogen Ligands

Doi:10.1021/ja00213a019
(1988)
Catalytic Transfer Hydrogenolysis of N-Benzyl Protecting Groups

Doi:10.1055/s-1987-27841
(1987)
Flavonoids syntheses. V. Synthesis of flavonoids with three hydroxy and four methoxy groups and their spectral properties

Doi:10.1248/cpb.35.660
(1987)
Reaction of Raney Nickel with Alcohols

Doi:10.1021/jo00249a007
(1988)

Article Doi