Direct Lithiation of Chalcogenachromones, -flavones, and -pyranones. The Interconversion and Electrophilic Capture of Ring-Opened and Ring-Closed Anions

Article abstract of DOI:10.1021/jo00241a015

The metalation of chalcogenapyranones, -chromones, and -flavones with lithium diisopropylamide generates 3-lithio derivatives which interconvert with their ring-opened anions.Through appropriate choices of electrophiles, both ring-opened and ring-closed p