
Tetrahedron Letters p. 4015 - 4018 (1987)
Update date:2022-08-03
Topics:
Lever, John R.
Dannals, Robert F.
Wilson, Alan A.
Ravert, Hayden T.
Wagner, Henry N., Jr.
Selective alkylation of 3-(O-t-butyldimethylsilyl)-6-(O-desmethyl)-diprenorphine with <11C>-methyl iodide followed by desilylation affords <11C>-diprenorphine labeled at the 6-methoxy position in 10percent yield with a specific activity of 1740 mCi/μmol at the end of a 30 minute synthesis.
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Doi:10.1002/adsc.202100141
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(1980)