Amberlyst-A21 as a New and Efficient Surface Catalyst for the Conjugate Addition of Nitroalkanes to Methyl Acrylate: An Improved Synthesis of Methyl 4-Nitro- and 4-Oxoalkanoates

DOI: 10.1055/s-1987-28054

Source and publish data:

Synthesis p. 711 - 713 (1987)

Update date:2022-08-04

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Authors:

Ballini, Roberto

Petrini, Marino

Rosini, Goffredo

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Article abstract of DOI:10.1055/s-1987-28054

Utilization of Amberlyst-A21 without solvent in the conjugate addition of nitroalkanes to methyl acrylate, affords 4-nitroalkanoic methyl esters in good yields.Successive Nef reaction, using potassium permanganate, provides functionalized 4-oxoalkanoic methyl esters.

Full text of DOI:10.1055/s-1987-28054

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