Highly stereoselective total synthesis of methynolide, the aglycon of the 12-membered macrolide antibiotic methamycin. I. synthesis of a Prelog-Djerassi lactone-type chiral intermediate from D-glucose

DOI: 10.1248/cpb.35.2184

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2184 - 2195 (1987)

Update date:2022-08-04

Topics: Asymmetric synthesis   NMR spectroscopy   Chromatography   Stereoselective synthesis   Total synthesis   Optical rotation   Deprotection   Protecting group   Retrosynthetic analysis   Macrolide   D-Glucose   Lactonization  

Authors:

Oikawa

Tanaka

Horita

et al.