Nonpeptide Angiotensin II Receptor Antagonist: N-imidazoles and Related Compounds as Potent Antihypertensives

DOI: 10.1021/jm00167a008

Source and publish data:

Journal of Medicinal Chemistry p. 1330 - 1336 (1990)

Update date:2022-07-31

Topics: Antagonist Compound ANGIOTENSIN II Potent Experimental Receptor antihypertensive

Authors:

Carini, David J.

Duncia, John V.

Johnson, Alexander L.

Chiu, Andrew T.

Price, William A.

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00167a008

A series of compounds has been synthesized and demonstrated to be antagonists of the angiotensin II (AII) receptor.These compounds are structurally related to the N-(benzamidobenzyl)imidazoles and extend the scope of this new class of nonpeptide AII antag

Full text of DOI:10.1021/jm00167a008

Products guided by the article

Product name:1H-Imidazole-5-carboxylic acid, 1-[[4-(phenylmethoxy)phenyl]methyl]-2-(propylthio)-, ethyl ester

Cas No:114773-16-9

R&D Labs maybe for 114773-16-9

Jiangxi Hessence Chemicals Co., Ltd.

Contact:+86 796 3511924

Address:Chengxi Industrial Park, Jishui County, Jiangxi Province 331600 China.
Chengdu King-tiger Pharm-chem. Tech. Co., Ltd

Contact:028-85317716

Address:Tianfu Life Science Park, No. 88 South Keyuan Road, Gaoxin District, Chengdu City, Sichuan Province, PRC.
Yuan Shi(SuQian)Biotechnology Co.,Ltd

website:http://www.yuanshibio.com

Contact:+86-527-84226672

Address:jiangsu suqian
Zipont chem(wuhan）Tech co.，Ltd

Contact:+86-27-87587198

Address:wuhan
SHUNYUANSHENG BIO-PHARMTECH CO., LTD

website:https://www.whsysbio.com

Contact:--

Address:Building 13, Liandong U Valley-Wuhan Economic Innovation Valley, No. 259, Xingsan Road, Shamao Street, Hannan District, Wuhan City, Hubei Province

Relevant to this article

SYNTHESIS OF (R)-1-BENZYLOXY-3-BUTEN-2-OL- A POTENTIAL CHIRAL SYNTHON FROM L-(+)-TARTARIC ACID: ITS APPLICATIONS IN NATURAL PRODUCT SYNTHESES

Doi:10.1016/S0040-4039(00)96898-9
(1987)
Study of the Reaction of Benzoyl Chloride and Sodium Dicarboxylate under Inverse Phase Transfer Catalysis

Doi:10.1246/bcsj.68.2165
(1995)
Synthesis of fisetin and 2′,4′,6′-trihydroxydihyrochalcone 4′-O-β-neohesperidoside based on site-selective deacetylation and deoxygenation

Doi:10.1080/09168451.2018.1467263
(2018)
Synthesis of 2-phenyl-5,6-dihydropyrano[2,3-c]pyrrole-4,7-dione derivatives

Doi:10.1134/S1070363208080331
(2008)
Doi:10.1039/jr9550003499
(1955)
A Novel One-Step Nickel-Mediated Synthesis of C6Ar6 Conjugated Hydrocarbons, Highly Substituted and Overcrowded Fulvenes and 3,4-Dimethylenecyclobutenes

Doi:10.1246/cl.1988.149
(1988)

Article Doi