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Nonpeptide Angiotensin II Receptor Antagonist: N-imidazoles and Related Compounds as Potent Antihypertensives

DOI: 10.1021/jm00167a008

Source and publish data:

Journal of Medicinal Chemistry p. 1330 - 1336 (1990)

Update date:2022-07-31

Topics: Antagonist   Compound   ANGIOTENSIN II   Potent   Experimental   Receptor   antihypertensive  

Authors:

Carini, David J.Carini, David J.

Duncia, John V.Duncia, John V.

Johnson, Alexander L.Johnson, Alexander L.

Chiu, Andrew T.Chiu, Andrew T.

Price, William A.Price, William A.

et al.et al.

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Article abstract of DOI:10.1021/jm00167a008

A series of compounds has been synthesized and demonstrated to be antagonists of the angiotensin II (AII) receptor.These compounds are structurally related to the N-(benzamidobenzyl)imidazoles and extend the scope of this new class of nonpeptide AII antag

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Full text of DOI:10.1021/jm00167a008

Products guided by the article

Product name:1H-Imidazole-5-carboxylic acid, 1-[[4-(phenylmethoxy)phenyl]methyl]-2-(propylthio)-, ethyl ester

Cas No:114773-16-9

114773-16-9

R&D Labs maybe for 114773-16-9

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