Nonpeptide Angiotensin II Receptor Antagonist: N-imidazoles and Related Compounds as Potent Antihypertensives

DOI: 10.1021/jm00167a008

Source and publish data:

Journal of Medicinal Chemistry p. 1330 - 1336 (1990)

Update date:2022-07-31

Topics: Antagonist Compound ANGIOTENSIN II Potent Experimental Receptor antihypertensive

Authors:

Carini, David J.

Duncia, John V.

Johnson, Alexander L.

Chiu, Andrew T.

Price, William A.

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00167a008

A series of compounds has been synthesized and demonstrated to be antagonists of the angiotensin II (AII) receptor.These compounds are structurally related to the N-(benzamidobenzyl)imidazoles and extend the scope of this new class of nonpeptide AII antag

Full text of DOI:10.1021/jm00167a008

Products guided by the article

Product name:1H-Imidazole-5-carboxylic acid, 1-[[4-(phenylmethoxy)phenyl]methyl]-2-(propylthio)-, ethyl ester

Cas No:114773-16-9

R&D Labs maybe for 114773-16-9

Nanjing Raise Pharmatech Co., Ltd

website:http://www.raisechem.com

Contact:+86-25-58649566

Address:B381,No.606,Ningliu Road,Jiangbei New Area,Nanjing,Jiangsu Province,China
Zhaodu Fine Chemical Plant

Contact:86-310-8067016

Address:East Fuhua Road,Tiexi Chemical Industrial Estate,Hebei,China
Hangzhou GreenCo Science & Technology Co., Ltd.

Contact:86-571-88257303

Address:1713 Room,Jingui Building,Gudun Road,Xihu District,Hangzhou,China
ZiBO KuoDing Trade company Ltd

website:http://www.sdzbkd.com

Contact:86-13361591822

Address:GongQingTuan road
Kono Chem Co.,Ltd

website:http://www.konochem.com

Contact:86-29-86107037-8015

Address:No.11 Daqing Road,Lianhu District,Xi’an 710082,China

Relevant to this article

SYNTHESIS OF (R)-1-BENZYLOXY-3-BUTEN-2-OL- A POTENTIAL CHIRAL SYNTHON FROM L-(+)-TARTARIC ACID: ITS APPLICATIONS IN NATURAL PRODUCT SYNTHESES

Doi:10.1016/S0040-4039(00)96898-9
(1987)
Study of the Reaction of Benzoyl Chloride and Sodium Dicarboxylate under Inverse Phase Transfer Catalysis

Doi:10.1246/bcsj.68.2165
(1995)
Synthesis of fisetin and 2′,4′,6′-trihydroxydihyrochalcone 4′-O-β-neohesperidoside based on site-selective deacetylation and deoxygenation

Doi:10.1080/09168451.2018.1467263
(2018)
Synthesis of 2-phenyl-5,6-dihydropyrano[2,3-c]pyrrole-4,7-dione derivatives

Doi:10.1134/S1070363208080331
(2008)
Doi:10.1039/jr9550003499
(1955)
A Novel One-Step Nickel-Mediated Synthesis of C6Ar6 Conjugated Hydrocarbons, Highly Substituted and Overcrowded Fulvenes and 3,4-Dimethylenecyclobutenes

Doi:10.1246/cl.1988.149
(1988)

Article Doi