Nonpeptide Angiotensin II Receptor Antagonist: N-imidazoles and Related Compounds as Potent Antihypertensives

DOI: 10.1021/jm00167a008

Source and publish data:

Journal of Medicinal Chemistry p. 1330 - 1336 (1990)

Update date:2022-07-31

Topics: Antagonist Compound ANGIOTENSIN II Potent Experimental Receptor antihypertensive

Authors:

Carini, David J.

Duncia, John V.

Johnson, Alexander L.

Chiu, Andrew T.

Price, William A.

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00167a008

A series of compounds has been synthesized and demonstrated to be antagonists of the angiotensin II (AII) receptor.These compounds are structurally related to the N-(benzamidobenzyl)imidazoles and extend the scope of this new class of nonpeptide AII antag

Full text of DOI:10.1021/jm00167a008

Products guided by the article

Product name:1H-Imidazole-5-carboxylic acid, 1-[[4-(phenylmethoxy)phenyl]methyl]-2-(propylthio)-, ethyl ester

Cas No:114773-16-9

R&D Labs maybe for 114773-16-9

ChangZhou XiaQing Chemical Co., Ltd.

Contact:+86-519-88721665

Address:3# Hengluo Road, Henglin Town, Changzhou City, Jiangsu Province，China
Shanghai Harvest Chemical Ind. Co., Ltd.

Contact:021-51385350

Address:ROOM 806-807, AI LI CHEN BUILDING, No.333 JINGXIANG ROAD, PUDONG DISTRICT, 201206, SHANGHAI
Anhui Xinyuan Technology Co.,Ltd

Contact:0086-559-3515800

Address:No.16 Zijin Rd, Circular Economic Zone, Huizhou District, Huangshan Anhui China
Jiangsu Dacheng Pharmaceutical and Chemical Co.,Ltd

Contact:+86-0517-87036900

Address:Chuzhou Chemical park, Huai'an, Jiangsu Province
Hebei Kangtai Pharmaceutical Co.,Ltd

Contact:+86-0317-3512963

Address:Wugang Road,Mengcun of Cangzhou City,Hebei Province ,China

Relevant to this article

SYNTHESIS OF (R)-1-BENZYLOXY-3-BUTEN-2-OL- A POTENTIAL CHIRAL SYNTHON FROM L-(+)-TARTARIC ACID: ITS APPLICATIONS IN NATURAL PRODUCT SYNTHESES

Doi:10.1016/S0040-4039(00)96898-9
(1987)
Study of the Reaction of Benzoyl Chloride and Sodium Dicarboxylate under Inverse Phase Transfer Catalysis

Doi:10.1246/bcsj.68.2165
(1995)
Synthesis of fisetin and 2′,4′,6′-trihydroxydihyrochalcone 4′-O-β-neohesperidoside based on site-selective deacetylation and deoxygenation

Doi:10.1080/09168451.2018.1467263
(2018)
Synthesis of 2-phenyl-5,6-dihydropyrano[2,3-c]pyrrole-4,7-dione derivatives

Doi:10.1134/S1070363208080331
(2008)
Doi:10.1039/jr9550003499
(1955)
A Novel One-Step Nickel-Mediated Synthesis of C6Ar6 Conjugated Hydrocarbons, Highly Substituted and Overcrowded Fulvenes and 3,4-Dimethylenecyclobutenes

Doi:10.1246/cl.1988.149
(1988)

Article Doi