Hydroxychalcones induce apoptosis in B16-F10 melanoma cells via GSH and ATP depletion

DOI: 10.1016/j.ejmech.2008.09.009

Source and publish data:

European Journal of Medicinal Chemistry p. 1630 - 1637 (2009)

Update date:2022-08-02

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Authors:

Navarini, Andreia Lilian Formento

Chiaradia, Louise Domeneghini

Mascarello, Alessandra

Fritzen, Marcio

Nunes, Ricardo Jose

Yunes, Rosendo Augusto

Creczynski-Pasa, Tania Beatriz

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Article abstract of DOI:10.1016/j.ejmech.2008.09.009

Searching for leading compounds of new drugs for cancer therapy, we studied the toxicity of 13 hydroxychalcones never tested before toward melanoma cell line (B16-F10). The compounds were obtained by aldolic condensation between aldehydes and hydroxylated

Full text of DOI:10.1016/j.ejmech.2008.09.009

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