Synthese, spektroskopische Charakterisierung und bakterizide Wirksamkeit neuer Organylbis(thiophenolato)bismut(III)-Komplexe

Article abstract of DOI:10.1016/0022-328X(87)80002-5

New organobis(thiophenolate)bismuth(III) derivatives C6H5Bi(SC6H4Cl-p)2 (I), CH3Bi(SC6H4NH2-p)2 (II) and CH3As(SC6H4NH2-p)2 (III) can be prepared by the reaction of phenyldibromobismuth(III), methyldibromobismuth(III) and -arsenic(III), prespectively, with stoichiometric amounts of lithium-p-chlorothiophenolate (for I), and lithium-p-aminothiophenolate.II reacts with an excess of iodomethane to form the bis(mercaptoanilinium) complex (2+)(I(-))2 (IV).Treating IV with adequate amounts of AgNO3 or TlNO3 yields the analogous nitrate derivative (2+)(NO3(1-))2 (V).The new compounds were characterized by elemental analysis, 1H NMR, IR and mass spectroscopy and some of the compounds were also characterized by vapour pressure moleculaar weight osmometry too.The microbiological effect of the organometallic arseno(III)- and bismuth(III)-bis(thiolates) I-IV was studied, the bismuth compounds generally inhibited bacterial growth more than the arsenic derivative.The aminothiophenolate complexes II and IV in particular were not inferior to the well-known organothiolatomercury(II) complexes with regard to their inhibition of bacterial growth.The hydrophilic mercaptoanilinium derivative IV has pogtential as a novel bactericide.