Enantioselectivity of muscarinic antagonists. Isomeric 2-cyclohexyl-2-phenyl-5-[(dimethylamino)methyl]-1,3-oxathiolane methiodides

DOI: 10.1021/jm00117a007

Source and publish data:

Journal of Medicinal Chemistry p. 1703 - 1708 (1988)

Update date:2022-07-29

Topics:

Authors:

Romanelli

Gualtieri

Valle Valle

Brasili Brasili

Angeli Angeli

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00117a007

The four isomers of 2-cyclohexyl-2-phenyl-5-[(dimethylamino)methyl]-1,3-oxathiolane methiodide were prepared. Their absolute configuration was attributed by means of X-ray crystallography and circular dichroism. The compounds were tested on rat bladder an

Full text of DOI:10.1021/jm00117a007

Products guided by the article

Product name:((2S,5R)-2-Cyclohexyl-2-phenyl-[1,3]oxathiolan-5-ylmethyl)-dimethyl-amine

Cas No:115114-18-6

R&D Labs maybe for 115114-18-6

Jiangsu Willing Bio-Tech Co ltd

website:http://www.willingbio.com/

Contact:+86 18796908173

Address:No 18 Guoqiao Road
Wuhan Hanye Chemical New Material Co.,Ltd

Contact:+86-27-85308141

Address:LiuDian, Panlongcheng Economic Development Zone, HuangPi district, Wuhan, Hubei 430311 P.R.China
CHINA MEHECO CORPORATION

Contact:+86-10-67147360/67107388

Address:No.18 Guangming Zhongjie, Chongwen District, Beijing, 100061, China
Shanghai Sinofluoro Scientific Co., Ltd

Contact:+86-21-64279360

Address:Room 1006,Building 3,#58 East Xinjian Road, Shanghai ,201100,China,
CHENGDU CHENLV HERB CO.,LTD

Contact:+86-28-88523492

Address:714rooms of Time Square, Pujiang County

Relevant to this article

Utilization of sequential palladium-catalyzed cross-coupling reactions in the stereospecific synthesis of trisubstituted olefins

Doi:10.1021/op900015g
(2009)
Synthesis of Dicyanovinyl-Substituted 1-(2-Pyridyl)pyrazoles: Design of a Fluorescent Chemosensor for Selective Recognition of Cyanide

Doi:10.1021/acs.joc.7b02460
(2017)
Design, synthesis and effect of triazole derivatives against some toxic activities of Bothrops jararaca venom

Doi:10.1007/s00044-020-02653-x
(2021)
Retro-inverso concept applied to the complete inhibitors of enkephalin-degrading enzymes

Doi:10.1021/jm00117a025
(1988)
Synthesis and SAR studies of neuritogenic gentiside derivatives

Doi:10.1248/cpb.c15-00795
(2016)
1,3,2-benzodiazaboroles with 1,3-pentafluorophenyl and tetrafluoropyridyl substituents as building blocks in luminescent compounds

Doi:10.1002/ejic.201300319
(2013)

Article Doi