Enantioselectivity of muscarinic antagonists. Isomeric 2-cyclohexyl-2-phenyl-5-[(dimethylamino)methyl]-1,3-oxathiolane methiodides

DOI: 10.1021/jm00117a007

Source and publish data:

Journal of Medicinal Chemistry p. 1703 - 1708 (1988)

Update date:2022-07-29

Topics:

Authors:

Romanelli

Gualtieri

Valle Valle

Brasili Brasili

Angeli Angeli

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Article abstract of DOI:10.1021/jm00117a007

The four isomers of 2-cyclohexyl-2-phenyl-5-[(dimethylamino)methyl]-1,3-oxathiolane methiodide were prepared. Their absolute configuration was attributed by means of X-ray crystallography and circular dichroism. The compounds were tested on rat bladder an

Full text of DOI:10.1021/jm00117a007

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Product name:((2S,5R)-2-Cyclohexyl-2-phenyl-[1,3]oxathiolan-5-ylmethyl)-dimethyl-amine

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