Journal of Medicinal Chemistry p. 2707 - 2714 (1990)
Update date:2022-08-04
Topics:
Iizuka, Kinji
Kamijo, Tetsuhide
Herada, Hiromu
Akahane, Kenji
Kubota, Tetsuhiro
et al.
A three-dimensional structure of the complex of human renin and the scissile site P4 Pro to P1' Val of angiotensinogen was deduced in order to design potent human renin inhibitors rationally.On the basis of this structure, an orally
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