AN ENANTIODIFFERENTIATING CONVERSION OF RACEMIC 1,3-ALKANEDIOLS INTO ENANTIOMERICALLY PURE MATERIALS

Article abstract of DOI:10.1016/S0040-4039(00)96641-3

Titanium tetrachloride promoted ring-cleavage reaction of a mixture of diastereomeric spiroketals derived from racemic 1,3-alkanediols and l-menthone, followed by benzoylation by Mitsunobu reaction, and the subsequent hydrolysis gave enantiomerically pure 1,3-alkanediols.