Structure-activity relationships among benextramine-related tetraamine disulfides. Chain length effect on α-adrenoreceptor blocking activity

DOI: 10.1021/jm00117a030

Source and publish data:

Journal of Medicinal Chemistry p. 1861 - 1866 (1988)

Update date:2022-07-29

Topics:

Authors:

Quaglia Quaglia

Brasili Brasili

Cristalli

Giardina

Picchio Picchio

Melchiorre

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00117a030

Several N'-substituted N,N''-(dithiodi-2,1-ethanediyl)bis(1,ω-alkanediamines) were prepared and evaluated for their blocking activity on α-adrenoreceptors in the isolated rat vas deferens and human blood platelets. The results were compared with those obt

Full text of DOI:10.1021/jm00117a030

Products guided by the article

Product name:N-(2-Methoxy-benzyl)-N'-(2-{2-[10-(2-methoxy-benzylamino)-decylamino]-ethyldisulfanyl}-ethyl)-decane-1,10-diamine

Cas No:115483-58-4

R&D Labs maybe for 115483-58-4

Shanghai Mintchem Development ., Ltd

Contact:0086 21 5190 8570

Address:R602,4#,89Nong, Mudan Road Pudong Shanghai China
Nantong LiKai Chemical Co.,Ltd

Contact:+86-513-89068669

Address:Jincheng Science Park
Beijing Greenchem Technology Co.,Ltd. ( Panjin Greenchem Technology Co.Ltd .)

website:http://www.bjgreenchem.com/

Contact:+86-427-6515887

Address:301,302, 3rd Floor, Building C-7, Dongsheng Science Park, Northern Territory, Zhongguancun, No. 66, Xixiaokou Road, Haidian District, Beijing
Hubei Onward Bio-Development Co., Ltd.

Contact:+86-718-8417012

Address:No.517,Shizhou Avenue,Enshi City,Hubei Province,China,445002
NINGBO PANGS CHEM INT’L CO.,LTD.

Contact:+86-574-27666845

Address:FLOOR 21,BUILDING NO.11,XIN TIAN DI,NO.689 SHI JI ROAD,NINGBO CHINA

Relevant to this article

2H-azirines as ligands: structural characterization of the first neutral and cationic (η⁵-C₅Me₅)Rh(III) 2H-azirine complexes

Doi:10.1002/zaac.200800098
(2008)
Excited-state photodynamics of perylene-porphyrin dyads. 5. tuning light-harvesting characteristics via perylene substituents, connection Motif, and three-dimensional architecture

Doi:10.1021/jp910705q
(2010)
An efficient and highly selective synthesis of (Z)-fluoroenol phosphates from hydroxy difluorophosphonates

Doi:10.1055/s-0028-1087803
(2009)
Doi:10.1039/jr9310000144
(1931)
Crystal solvates of tetrakis(3,5-di-t-butylphenyl)-porphyrinates Mn(III), Ni(II) and Zn(II) with pyridine

Doi:10.1007/s10973-008-9012-4
(2008)
Cellular Activity of New Small Molecule Protein Arginine Deiminase 3 (PAD3) Inhibitors

Doi:10.1021/acsmedchemlett.6b00215
(2016)

Article Doi