Structure-activity relationships among benextramine-related tetraamine disulfides. Chain length effect on α-adrenoreceptor blocking activity

DOI: 10.1021/jm00117a030

Source and publish data:

Journal of Medicinal Chemistry p. 1861 - 1866 (1988)

Update date:2022-07-29

Topics:

Authors:

Quaglia Quaglia

Brasili Brasili

Cristalli

Giardina

Picchio Picchio

Melchiorre

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Article abstract of DOI:10.1021/jm00117a030

Several N'-substituted N,N''-(dithiodi-2,1-ethanediyl)bis(1,ω-alkanediamines) were prepared and evaluated for their blocking activity on α-adrenoreceptors in the isolated rat vas deferens and human blood platelets. The results were compared with those obt

Full text of DOI:10.1021/jm00117a030

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