Practical Synthesis of Some Versatile Chiral Building Blocks from (D)-Mannitol

DOI: 10.1055/s-1986-31653

Source and publish data:

Synthesis p. 403 - 406 (1986)

Update date:2022-07-29

Topics:

Authors:

Takano, Seiichi

Kurotaki, Ayako

Takahashi, Michiyasu

Ogasawara, Kunio

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1055/s-1986-31653

The three chiral building blocks ethyl 4,5-O-isopropylidene-(E)-(S)-4,5-dihydroxy-2-pentenoate <1,3-dioxolane derivative (E)-(S)-1a>, (S)-5-hydroxy-4-pentanolide <(S)-2a>, and (S)-5-hydroxy-2-penten-4-olide <(S)-3a> are conveniently prepared from 1,2:5,6-di-O-isopropylidene-D-mannitol (4) via a glycol cleavage and Horner-Emmons reaction sequence.

Full text of DOI:10.1055/s-1986-31653

Products guided by the article

Product name:(3R/S,4S)-5-Hydroxy-3-phenylthio-4-pentanolide

Cas No:115730-99-9

R&D Labs maybe for 115730-99-9

Jinan Finer Chemical Co., Ltd

website:http://www.finerchem.com

Contact:+86-531-88989536

Address:New Material Industry Park, Jinan Ciyt, China
Wuhan Shengmao Corp

website:http://www.shengmaochem.com

Contact:86-27-82853423, 82819281

Address:Rm 202, A Unit Huaqiao Building No. 2, Lihuangpi Road, Wuhan, China
VanderArk International Limited

Contact:86-10-82437576

Address:Qing He
LianYunGang Chiral Chemical(CHINA) CO.,LTD

Contact:+86-518-83616958 +86-519-82884848

Address:LianYunGang Chemical Industry Park (JiangSu)
Fujian Wanke Pharmaceutical Co., LTD.

Contact:+86-598-5026002

Address:Economic development zone,jiangle county

Relevant to this article

Preparation and reactions of N-thioformyl peptides from amino thioacids and isonitriles

Doi:10.1016/j.tetlet.2009.02.205
(2009)
Inhibition of carbonic anhydrase isozymes with benzene sulfonamides incorporating thio, sulfinyl and sulfonyl glycoside moieties

Doi:10.1016/j.bmcl.2009.02.086
(2009)
CuSO₄ nanoparticles loaded on carboxymethylcelulose/polyaniline composites: A highly efficient catalyst with enhanced catalytic activity in the synthesis of propargylamines, benzofurans, and 1,2,3-triazoles

Doi:10.1002/aoc.6349
(2021)
Tetraphenylphosphonium bis(2-thioxo-1,3-dithiole-4,5-dithiolato)- aurate(III) acetone solvate and ethyltriphenylphosphonium bis(2-thioxo-1,3- dithiole-4,5-dithiolato)aurate(III)

Doi:10.1107/S010827010706074X
(2008)
Spectral emission properties of 4-aryloxy-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]quinolines

Doi:10.1016/j.saa.2009.02.026
(2009)
A new palladium(II)-catalyzed [3,3] aza-Claisen rearrangement of 3-allyloxy-5-aryl-1,2,4-oxadiazoles

Doi:10.1016/j.tetlet.2010.12.058
(2011)

Article Doi