One-pot conversion of α-ureido and α-thioureido esters to imidazol-2-ones and imidazole-2-thiones

Article abstract of DOI:10.1055/s-1997-6138

4-Hydroxyimidazolidin-2-ones and 4-hydroxyimidazolidine-2-thiones are obtained by treatment of N-(aminocarbonyl)-α-amino esters and N-(aminothiocarbonyl)-α-amino esters with diisobutylaluminum hydride (DIBAH). These substances are transformed to imidazol-2-ones and imidazole-2-thiones upon acidic workup.