Synlett p. 521 - 522 (1997)
Update date:2022-08-04
Topics:
Markwalder, Jay A.
Pottorf, Richard S.
Seitz, Steven P.
4-Hydroxyimidazolidin-2-ones and 4-hydroxyimidazolidine-2-thiones are obtained by treatment of N-(aminocarbonyl)-α-amino esters and N-(aminothiocarbonyl)-α-amino esters with diisobutylaluminum hydride (DIBAH). These substances are transformed to imidazol-2-ones and imidazole-2-thiones upon acidic workup.
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