TOTAL ENANTIOSPECIFIC SYNTHESIS OF 12(R)-HETE

DOI: 10.1016/S0040-4039(00)96908-9

Source and publish data:

Tetrahedron Letters p. 6543 - 6544 (1987)

Update date:2022-08-04

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Authors:

Taffer, Ira M.

Zipkin, Robert E.

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Article abstract of DOI:10.1016/S0040-4039(00)96908-9

A total synthesis of 12(R)-hydroxy-5,8,14-cis-10-trans-eicosatetraenoic acid <12(R)-HETE> was accomplished via a short, efficient, enantiospecific route.

Full text of DOI:10.1016/S0040-4039(00)96908-9

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Product name:(5Z,8Z,10E)-(R)-12-(tert-Butyl-diphenyl-silanyloxy)-icosa-5,8,10-trien-14-ynoic acid methyl ester

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