
Tetrahedron p. 3633 - 3638 (1988)
Update date:2022-08-03
Topics: Purification Reaction Conditions Enzyme Selection Reaction Monitoring Analytical Techniques Quenching Kinetic Control Scaling up
Bratovanova, E. K.
Stoineva, I. B.
Petkov, D. D.
The yield and its time-dependence in acylenzyme mechanism-based enzymic peptide synthesis are controlled by the proteinase kinetic specificity.The maximum yield is limited by a non equilibrium constant Kmax.Both Kmax and the time, t<
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Doi:10.1016/S0277-5387(00)81755-6
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