Sialylation using N-glycolylneuraminyl phosphite donors to synthesize Neu5Gc-containing glycans

Article abstract of DOI:10.1016/j.carres.2009.03.004

Efficient sialylations using N-glycolylneuraminic acid (Neu5Gc) phosphite donors having an acetyl or benzyl group on the glycolyl moiety are described in the synthesis of Neu5Gc-containing glycans. Both phosphite donors 1 and 2 were readily coupled with p