Studies on cerebral protective agents. VI. Synthesis of novel 4-(4- nitrobenzoyl)pyrimidine and related compounds with anti-anoxic activity

DOI: 10.1248/cpb.42.1279

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1279 - 1285 (1994)

Update date:2022-09-26

Topics: Synthesis Novel Experimental studies Protective agents

Authors:

Ohkubo Ohkubo

Kuno Kuno

Sakai Sakai

Sugiyama

Takasugi

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Article abstract of DOI:10.1248/cpb.42.1279

Novel pyrimidine derivatives, possessing linkages between the aryl group and the pyrimidine nucleus at the C-4 position, were prepared and tested for anti-anoxic (AA) activity in mice. Among them, 5-(4-methylpiperazin-1- ylcarbonyl)-4-(4-nitrobenzoyl)-2-p

Full text of DOI:10.1248/cpb.42.1279

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