Journal of Medicinal Chemistry p. 105 - 118 (1989)
Update date:2022-08-03
Topics:
Walsh, David A.
Franzyshen, Stephen K.
Yanni, John M.
A series of 4-(diarylhydroxymethyl)-1-<3-(aryloxy)propyl>piperidines was synthesized and evaluated for antiallergy activity.Several analogues had potent activity in the passive foot anaphylaxis (PFA) assay, an IgE-mediated model useful in the detection of compounds possessing antiallergic activity.In particular 1-<4-<3-<4-
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