A New Effective and Convenient Route to Fluorinated Nitrogen Heterocyclic Compounds by the Use of Enol Phosphates Derived from F-Alkyl Ketones

DOI: 10.1246/cl.1988.819

Source and publish data:

Chemistry Letters p. 819 - 822 (1988)

Update date:2022-08-05

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Authors:

Ishihara, Takashi

Okada, Yoshiji

Kuroboshi, Manabu

Shinozaki, Takao

Ando, Teiichi

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Article abstract of DOI:10.1246/cl.1988.819

The treatment of F-alkyl ketones with sodium diethyl phosphite in tetrahydrofuran at -10 to 0 deg C gave high yields of 1-substituted F-1-alkenyl phosphates, which readily reacted with amidine of hydrazine derivatives at room temperature to afford the cor

Full text of DOI:10.1246/cl.1988.819

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