
Journal of Heterocyclic Chemistry p. 651 - 654 (1988)
Update date:2022-08-03
Topics: Synthesis Chiral Ribavirin Experimental
Vemishetti
Leiby
Abushanab
Panzica
A practical and efficient synthesis of ethyl 1,2,4-triazole-3-carboxylate (6a, R'' = H) from ethyl carboethoxyformimidate hydrochloride is described. Alkylation of this heterocycle with the chloromethyl ethers of 1,3-O-dibenzylbutane-1,2R,3S-triol and 1,3
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(1988)