Total synthesis of globotriaosylceramide (Gb3) and lysoglobotriaosylceramide (lysoGb3)

Article abstract of DOI:10.1016/0008-6215(90)84079-A

We have recently reported a highly efficient and stereocontrolled synthesis of globotriaosylceramide (Gb₃, 1) in optically pure form.Key to our synthetic strategy was the implementation of the two-stage activation of thioglycosides for formatio