Journal of Organic Chemistry p. 428 - 431 (1989)
Update date:2022-07-30
Topics:
Lee, Ho H.
Cain, Bruce F.
Denny, William A.
Buckleton, John S.
Clark, George R.
The synthesis of the masked aminopyrazolecarboxylic acid synthons (11a,b and 12a,b) from pyrazole-3,5-dicarboxylic acid (6) and the determination of their structures by X-ray crystallography are detailed.The compounds are useful for the synthesis of polypyrazolecarboxamides analogous to the DNA minor groove binding antibiotics distamycin A and netropsin.
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