Tetrahedron p. 3195 - 3202 (1988)
Update date:2022-08-03
Topics:
Gribble, Gordon W.
Barden, Timothy C.
Johnson, David A.
A synthesis protocol involving beta-lithiation of 2-(2-pyridinyl)indoles(4<*>5) and subsequent reaction with bromoacetaldehyde leads to the indolo<2,3-a>quinolizine (1) ring system.Application of this methodology to 2-(2-pyridinyl)indole 17, which is prepared via Taylor-Boger triazine Diels-Alder annulation chemistry, affords the zwitterionic indole alkaloid sempervirine (3).
View MoreContact:+86-515-88356562
Address:No.2, West Daqing Road, Yancheng, Jiangsu, China
Contact:
Address:ROOM 1715, No#345 Jin Xiang Road, Pudong District
Contact:+86-371-86058576
Address:NO.32, Jingsan Road, Zhengzhou, China
Zhejiang Haizhou Pharmaceutical Co., Ltd.
website:https://www.haizhoupharma.com/
Contact:+86-576-88221016
Address:No. 19, Donghai 5th Avenue, Yanhai Industrial Zone, Linhai, Zhejiang, China
WUXI KINGHAN BIO-MEDICAL&CHEMICAL INC.
Contact:13861062998
Address:Room 1316,No.1619 Huishan Avenue,Wuxi,China
Doi:10.1248/cpb.36.1139
(1988)Doi:10.1021/jo901350j
(2009)Doi:10.1055/s-0029-1217329
(2009)Doi:10.1002/ejic.200800524
(2008)Doi:10.1248/cpb.39.1736
(1991)Doi:10.1016/S0040-4039(00)87824-7
(1988)
