2(1H)-Quinolinones with cardiac stimulant activity. 2. Synthesis and biological activities of 6-(N-linked, five membered heteroaryl) derivatives

DOI: 10.1021/jm00123a011

Source and publish data:

Journal of Medicinal Chemistry p. 575 - 583 (1989)

Update date:2022-07-30

Topics:

Authors:

Alabaster

Bell Bell

Campbell

Ellis Ellis

Henderson

Morris Morris

Roberts Roberts

Ruddock Ruddock

Samuels Samuels

Stefaniak

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Article abstract of DOI:10.1021/jm00123a011

A series of 6-(N-linked, five membered heteroaryl)-2(1H)-quinolinone derivatives was synthesized and evaluated for cardiotonic activity. Most compounds were prepared by sulfuric acid catalyzed cyclization of an N-(4-heteroarylphenyl)-3-ethoxypropenamide o

Full text of DOI:10.1021/jm00123a011

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