3-Aminopyridazine derivatives with atypical antidepressant, serotonergic, and dopaminergic activities

DOI: 10.1021/jm00123a004

Source and publish data:

Journal of Medicinal Chemistry p. 528 - 537 (1989)

Update date:2022-09-26

Topics:

Authors:

Wermuth Wermuth

Schlewer

Bourguignon

Maghioros

Bouchet Bouchet

Moire Moire

Kan Kan

Worms Worms

Biziere Biziere

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Article abstract of DOI:10.1021/jm00123a004

Minaprine [3[(β-morpholinoethyl)amino]4-methyl-6-phenylpyridazine dihydrochloride] is active in most animal models of depression and exhibits in vivo a dual dopaminomimetic and serotoninomimetic activity profile. In an attempt to dissociate these two effe

Full text of DOI:10.1021/jm00123a004

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