3-Aminopyridazine derivatives with atypical antidepressant, serotonergic, and dopaminergic activities

DOI: 10.1021/jm00123a004

Source and publish data:

Journal of Medicinal Chemistry p. 528 - 537 (1989)

Update date:2022-09-26

Topics:

Authors:

Wermuth Wermuth

Schlewer

Bourguignon

Maghioros

Bouchet Bouchet

Moire Moire

Kan Kan

Worms Worms

Biziere Biziere

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00123a004

Minaprine [3[(β-morpholinoethyl)amino]4-methyl-6-phenylpyridazine dihydrochloride] is active in most animal models of depression and exhibits in vivo a dual dopaminomimetic and serotoninomimetic activity profile. In an attempt to dissociate these two effe

Full text of DOI:10.1021/jm00123a004

Products guided by the article

Product name:CM 30070

Cas No:118269-75-3

R&D Labs maybe for 118269-75-3

Henan zhongda Biological Engineering Co., Ltd

Contact:86-28-18109029985

Address:shenzhou road,xuedian industrial estate,zhengzhou city,henan province CHN
Shanghai Bosman Industrial Co., Ltd

Contact:86-21-63065878-8006

Address:Rm907, No.1611, North Sichuan Road, Hongkou District, Shanghai, 200080 China
Tianjin Jiuri New Materials Co., Ltd.

Contact:+86-22-58889220

Address:C-5/6, Vison Hill, No.1 Gonghua Road, Huayuan Hi-tech Park, Tianjin, China.
Changzhou Qidi Chemical Co., Ltd

website:http://www.czqdhg.com/

Contact:86-519-83382137

Address:128-1-16# HuaYuan Street,Hutang Town,Wujin District,Changzhou City,P.R.China.
Quhua Zhongxing Refrigeration Technology Co.,Ltd.

Contact:+86-5708886618

Address:318 Bulding 2, No.866 Quhua Rd.,Kecheng District

Relevant to this article

Synthesis of structurally simplified analogues of pancratistatin: Truncation of the cyclitol ring

Doi:10.1021/jo901494r
(2009)
Design, synthesis and evaluation of a novel cyclohexanamine class of neuropeptide Y Y1 receptor antagonists

Doi:10.1016/j.bmcl.2009.06.050
(2009)
Synthesis, optical resolution and absolute configuration of inherently chiral calixarene carboxylic acids

Doi:10.1016/j.tet.2009.06.039
(2009)
Synthesis of [1,2,4]triazolo[3,4-b][1,3]thiazine-5-carboxylates via one-pot reaction of N-substituted-hydrazino-carbothioamides with diethyl maleate

Doi:10.1002/jhet.173
(2009)
SUBSTITUENT AND COORDINATION EFFECTS IN SINGLET REACTIONS OF 3-DIAZO-3H-1,2,4-TRIAZOLES WITH SUBSTITUTED BENZENES AND NITRO COMPOUNDS

Doi:10.1016/S0040-4039(00)95476-5
(1987)
Formation of chiral C(sp³)-C(sp) bond by allylic substitution of secondary allylic picolinates and alkynyl copper reagents

Doi:10.1021/jo901728b
(2009)

Article Doi