Tetrahedron Letters p. 4359 - 4362 (1990)
Update date:2022-07-31
Topics:
Barker
Campbell
Jenkins
A brief and efficient new synthesis of 2-substituted 6-[1(R)-hydroxyethyl]-penems is described. The key step involves reaction of an azetidin-2-one-4-disulphide with either stabilized or unstablized phosphoranes, giving ylids which cyclize with the 1-oxalimide group to give 2-substituted penems.
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(2009)Doi:10.1016/j.bmcl.2009.05.067
(2009)Doi:10.1515/bchm2.1960.319.1.143
(1960)Doi:10.1021/jo00267a010
(1989)
