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Synthesis and antitumor activity of lipid A analogs having a phosphonooxyethyl group with α- or β-configuration at position 1

DOI: 10.1248/cpb.38.3366

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 3366 - 3372 (1990)

Update date:2022-08-05

Topics: Synthesis   NMR spectroscopy   Stereochemistry   Analog   Mass spectrometry (MS)   Cytotoxicity   HPLC (high-performance liquid chromatography)   Purification   In vitro Testing   In Vivo Testing   Antitumor Activity   Structure-Activity Relationship (SAR)   Biological Activity   Phosphorylation  

Authors:

KusamaKusama

SogaSoga

ShioyaShioya

NakayamaNakayama

NakajimaNakajima

OsadaOsada

OnoOno

KusumotoKusumoto

ShibaShiba

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Article abstract of DOI:10.1248/cpb.38.3366

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Full text of DOI:10.1248/cpb.38.3366

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Products guided by the article

Product name:2-(diphenylphosphonooxy)ethyl 3-O-<(R)-3-benzyloxytetradecanoyl>-2-<(R)-3-benzyloxytetradecanoylamino>-2-deoxy-6-O-<2-deoxy-4-O-diphenylphosphono-2-<(R)-3-dodecanoyloxytetradecanoylamino>-3-O-<(R)-3-tetradecanoyloxytetradecanoyl>-β-D-glucopyranosyl>...

Cas No:118638-33-8

118638-33-8

R&D Labs maybe for 118638-33-8

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