Synthesis p. 556 - 557 (1988)
Update date:2022-08-02
Topics:
Datta, A.
Ila, H.
Junjappa, H.
The 3-oxodithioesters 1 and 3-oxothioamides 6 are shown to undergo base catalyzed S-alkylation with methyl 4-bromocrotonate followed by intramolecular condensation to give the corresponding methyl 3-(3,4-disubstituted 5-alkylthio/amino-2-thienyl) propenoates 5 and 7 in good yields.
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